An activity labelled molecular networking strategy-assisted discovery of antiplatelet aggregation-active components from Allium chinense G. Don (opens in new tab)

IntroductionAllium chinense G. Don (ACGD) is a famous Chinese medicine that shares homology with medicine and food. However, the mechanism of ACGD-related components in antiplatelet aggregation remains unclear.MethodsThis study identified steroidal saponins using a targeted molecular networking (TMN) approach and explored the mechanism of antiplatelet aggregation.ResultsACGD samples (1 mg/mL) extracted using different solvents (water, 30% methanol, 50% methanol, 70% methanol, and 100% methano...