Dynamics and compositional profiles of human milk oligosaccharides in mothers with gestational diabetes mellitus across lactation (opens in new tab)

PurposeThis study aimed to systematically clarify the changes in the concentrations of human milk oligosaccharides (HMOs) in mothers with gestational diabetes mellitus (GDM) and the differences from healthy mothers.MethodsA total of 156 human milk samples were collected from 50 mothers (26 healthy mothers and 24 GDM mothers) in Danyang City at different lactation stages (0–7 days, 8–14 days, 1 month, and 3 months postpartum). By using the method of UPLC–MS/MS to analyse the concentration of H...