The Triglyceride-Glucose-Chinese Visceral Adiposity Index (TyG-CVAI) outperforms other insulin resistance indices in its association with cardiovascular-kidney-metabolic syndrome severity in type 2 diabetes: a comparative study (opens in new tab)

BackgroundThe Cardiovascular-Kidney-Metabolic (CKM) syndrome integrates the pathophysiology of metabolic disease, chronic kidney disease, and cardiovascular disease. Accessible biomarkers for risk stratification are urgently needed, especially in high-risk populations like patients with type 2 diabetes (T2D). We compared the novel Triglyceride-Glucose-Chinese Visceral Adiposity Index (TyG-CVAI) against established insulin resistance (IR) surrogates for its association with CKM severity in T2D...