Safety and tolerability of Ashwagandha (Withania somnifera) root extract in healthy adults: a prospective, non-comparative study (opens in new tab)

Background and aimAshwagandha, adaptogenic herb traditionally used to enhance resilience to stress and promote overall well-being. Although its safety at conventional doses is well established, evidence regarding the safety of higher doses in healthy adults remains limited. The present study aimed to evaluate the safety and tolerability of Ashwagandha root extract (ARE) administered at a dose of 2000 mg/day in healthy adults over 12 weeks.MethodsThis was a prospective, single-arm, non-compara...