Proteomic profiling in personalized nutrition: a systematic review and methodological frameworks of randomized controlled trials (opens in new tab)

BackgroundPersonalized nutrition aims to tailor dietary advice by accounting for interindividual variability. However, the application and integration of proteomic profiling within dietary intervention studies have not yet been systematically mapped.MethodsA PRISMA-aligned systematic review (PROSPERO CRD420251011886) of randomized controlled trials (RCTs) was conducted searching PubMed, Embase, and Scopus. We included RCTs with a dietary intervention incorporating a genotype- and/or phenotype...