Association of prognostic nutritional index with fecal incontinence and fecal incontinence severity index in individuals with osteoporosis: mediating roles of C-reactive protein and gamma-glutamyl transferase (opens in new tab)

BackgroundMalnutrition is increasingly recognized as a contributor to both osteoporosis and gastrointestinal dysfunction. The prognostic nutritional index, derived from serum albumin and lymphocyte counts, reflects nutritional and immune status. However, its association with fecal incontinence in osteoporotic patients remains unexplored.MethodsThis cross-sectional study included osteoporotic patients from one Chinese tertiary hospital between 2021 and 2025. FI was assessed using the bowel hea...