Dynamic nutritional trajectories and deterioration risk in esophageal cancer radiotherapy: a prospective study (opens in new tab)

BackgroundNutritional deterioration (ND) during radiotherapy (RT) for esophageal cancer is common, yet the optimal timing for proactive supportive care remains unclear. We characterized time-resolved nutritional trajectories, examined baseline factors associated with deterioration, and translated the findings into a patient-facing digital prototype.MethodsIn this prospective longitudinal cohort, 123 patients underwent nutritional assessment at five timepoints (admission, RT1, RT14, RT20, and ...