Prognostic impact of the combined effects of lipoprotein(a) and homocysteine in patients with premature myocardial infarction: a prospective cohort study (opens in new tab)

BackgroundLipoprotein(a) [Lp(a)] is a causal driver of atherosclerosis, yet the interaction between Lp(a)-driven lipid accumulation and a prothrombotic state induced by hyperhomocysteinemia has not been systematically investigated in this high-risk population. From a clinical nutrition perspective, homocysteine (HCY) is a critical modifiable metabolite influenced by B vitamins and folate, making this interaction particularly relevant for dietary or supplementation strategies. This study aims ...