Cumulative exposure and patterns of the cholesterol–HDL-C–glucose index and risk of new-onset cardiometabolic multimorbidity: 9-year longitudinal evidence from CHARLS (opens in new tab)

BackgroundThe cholesterol–HDL-C–glucose (CHG) index has been proposed as an integrated marker of glucose–lipid metabolic dysfunction. However, the associations of long-term CHG exposure and its temporal patterns with new-onset cardiometabolic multimorbidity (CMM) remain unclear, particularly among middle-aged and older adults.MethodsWe used data from the China Health and Retirement Longitudinal Study (CHARLS) and included participants aged 45 years or older without baseline CMM. Cumulative CH...