Frontiers

Low 1,25-dihydroxyvitamin D levels are associated with severe COVID-19: an observational study in hospitalized patients (opens in new tab)

BackgroundThis study aimed to evaluate the association of serum 25-hydroxyvitamin D (25(OH)D) and 1,25-dihydroxyvitamin D (1,25(OH)2D) levels with clinical severity and mortality among hospitalized patients with moderate and severe COVID-19.MethodsA total of 185 adult patients (≥18 years) with confirmed SARS-CoV-2 PCR positivity and without chronic kidney disease, admitted between March and May 2020, were included. Clinical characteristics, laboratory parameters, and serum 25(OH)D and 1,25(OH...

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