Frontiers

Nonlinear dose–response relationship between serum ferritin and anemia in Chinese children: a matched case-control study (opens in new tab)

ObjectivesThis study aimed to investigate the dose–response relationship between serum ferritin (SF) and anemia risk in Chinese children and adolescents, with a specific focus on potential non-linearity and effect modification by sex.MethodsA 1:3 age- and sex-matched case–control study was conducted, comprising 175 anemia cases and 525 controls selected from a national school-based surveillance system. Anemia was diagnosed using WHO altitude-adjusted hemoglobin cutoffs. SF was measured by ele...

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