Frontiers

Dynamic vitamin D trajectories and their prognostic value in breast cancer: a group-based trajectory modeling study (opens in new tab)

Breast cancer represents the most frequently diagnosed malignancy and a leading cause of cancer-related mortality among women globally, with substantial prognostic heterogeneity that underscores the urgent need for robust prognostic biomarkers to guide personalized clinical management. Although accumulating evidence has linked vitamin D status to breast cancer progression, most existing studies have relied on static single measurements of serum vitamin D, leading to inconsistent findings, whi...

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