Serum lipid profiles and risk of depression: a UK Biobank prospective cohort study (opens in new tab)

BackgroundThe relationship between serum lipids and depression is poorly characterized, with existing studies yielding inconsistent results. We aim to prospectively investigate the associations between 11 serum lipid traits and risk of incident depression in a large cohort from the UK Biobank.MethodsThe primary exposures were baseline serum concentrations of Apolipoprotein A (ApoA), Apolipoprotein B (ApoB), HDL-C, LDL-C, triglyceride, total cholesterol, total esterified cholesterol, total fre...