Ginsenoside Rb1 alleviates overtraining-induced oxidative stress in mouse liver by stimulating mitophagy via Nrf2 pathway (opens in new tab)

IntroductionModerate exercise induces beneficial adaptive responses in the body, whereas sustained high-intensity exercise without adequate recovery leads to overtraining syndrome (OTS), a pathological condition associated with multiple organ damage, especially liver injury. Currently, safe and effective nutritional interventions for OTS-induced liver injury remain limited. This study aimed to investigate the protective effect of ginsenoside Rb1 (Gs-Rb1), the primary bioactive component of gi...