Frontiers

Association of metabolic score for insulin resistance with gestational diabetes mellitus: a systematic review and meta-analysis (opens in new tab)

ObjectiveThis study aimed to systematically evaluate the association between the Metabolic Score for Insulin Resistance (METS-IR) and the risk of gestational diabetes mellitus (GDM).MethodsA systematic search was conducted in PubMed, Embase, Web of Science, and the Cochrane Library up to March 2026. Two independent reviewers completed study screening, data extraction, and quality assessment. Cohort studies were evaluated with the Newcastle-Ottawa Scale, and cross-sectional studies were assess...

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