Combined associations of the frailty index and CHG index with cardiometabolic multimorbidity: a longitudinal study from the CHARLS cohort (opens in new tab)

IntroductionFrailty and metabolic dysfunction are major contributors to cardiometabolic multimorbidity (CMM). However, the joint influence of frailty and insulin resistance on the onset of CMM is still insufficiently understood. This research aimed to examine the association between FI-CHG [a novel integrative metric combining the frailty index (FI) and the cholesterol-high-density lipoprotein-glucose (CHG) index] and incident CMM.MethodOverall, 8,543 participants aged ≥45 years without CMM a...