Beyond adherence: refractory dyslipidaemia, the mediterranean diet, and the case for personalized diet-drug complementarity (opens in new tab)

Cardiovascular disease (CVD) remains the leading cause of death worldwide, and atherogenic dyslipidaemia is one of its most modifiable drivers. The Mediterranean diet (MedDiet) is among the most extensively studied and best-supported dietary patterns for cardiovascular protection, yet meta-analyses show only modest and heterogeneous effects on the conventional lipid panel: typically 5%−15% reductions in LDL cholesterol, 10%−20% reductions in triglycerides and 3%−6% increases in HDL cholestero...