AI digital-twin ecosystem translating gut-microbiome–neuroimmune signals into precision sleep–mood interventions (opens in new tab)

We present a novel AI-powered “gut–brain–sleep” digital-twin nursing ecosystem (G-B-S DT-N) that translates microbiome and neuroimmune signals into precision interventions for sleep and mood disorders. The ecosystem integrates four key layers: Microbiome Dynamics, Neuro-immune Interface, Sleep-Cognition-Emotion Circuits, and Person-Nurse-Environment Triad. These layers leverage multi-omics data, EEG sleep microstructure, real-time sensors, and EMR feeds to create a dynamic, patient-specific a...