Frontiers

The trajectories of Demoralization Syndrome and its related factors among elderly patients with end-stage kidney disease: a longitudinal study (opens in new tab)

ObjectiveElderly ESKD patients frequently experience a range of psychosocial difficulties, with Demoralization Syndrome (DS) being especially prevalent. This study sought to delineate distinct longitudinal trajectories of DS and to examine factors associated with trajectory membership.MethodsA prospective longitudinal cohort of 363 elderly ESKD patients was recruited from Department of Nephrology in grade a hospital in Anhui, China from January 2023 to December 2025. DS was measured 4 time po...

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