Frontiers

Homocysteine and cognitive function in depression: a systematic review and meta-analysis (opens in new tab)

ObjectiveThis study aimed to assess the association between homocysteine (Hcy) levels and cognitive function in individuals with depression using a systematic review and meta-analysis.MethodsWe searched PubMed, Web of Science, EMBASE, the Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Data, and the Chinese Science and Technology Journal Database (VIP) for studies reporting Hcy levels and cognitive outcomes in patients with depression from inception to December 2025....

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