Abnormalcerebral-limbic functional connectivity between bipolar mania and bipolar depression under resting state (opens in new tab)

ObjectivePrevious research has identified aberrant functional connectivity (FC) in the neural circuits of patients with bipolar mania (BD-M) and bipolar depression (BD-D), yet the specificity of these FC patterns to each mood state remains unelucidated. This study was designed to compare the cerebral-limbic FC characteristics among BD-M, BD-D patients and healthy control (HC) subjects.MethodResting-state functional magnetic resonance imaging (fMRI) was performed on 30 BD-M patients, 31 BD-D p...