“Homicide and Zonisamide”: a review of the literature and illustrative case report on second and third generation antiseizure medications and psychiatric effect... (opens in new tab)

IntroductionCerebral cavernous malformations (CCMs) are vascular lesions that can cause focal epilepsy due to local hemosiderin deposition, gliosis, and cortical irritation. Epileptic seizures attributable to CCMs contribute significantly to morbidity and often require long-term management with antiseizure medications (ASMs), but the psychiatric side effect profiles of ASMs remain underreported in the literature.Case reportHerein, we present a case report of a patient with homicidal ideation ...