Frontiers

Circulating microRNA molecular signatures converge with erythroid phenotypes and iron homeostasis in pediatric tic disorders (opens in new tab)

IntroductionTic disorders (TDs) are common neurodevelopmental conditions with unclear pathogenesis and a lack of objective biomarkers. This study aimed to explore the associations among circulating microRNAs (miRNAs), erythroid phenotypes, iron homeostasis, and pediatric TD.MethodsA total of 30 TD children and 10 healthy controls were enrolled. Serum levels of five candidate miRNAs, erythroid parameters, and iron metabolism indicators were detected. In this study, serum levels of five candida...

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