“Brain not right” and “lonely in a crowd”: unveiling the central architecture of psychopathology in obsessive-compulsive disorder (opens in new tab)

BackgroundThe co-occurrence of obsessive-compulsive disorder (OCD) and psychotic-like symptoms suggests the existence of the “obsessive-schizophrenic spectrum”, and this study uses network analysis to explore their interaction mechanism.MethodsA total of 528 patients with obsessive-compulsive disorder (OCD) were included. A symptom network was constructed based on the Yale-Brown ObsessiveCompulsive Scale (Y-BOCS), Symptom Checklist-90 (SCL-90), Self-Rating Anxiety Scale (SAS), and Self-Rating...