ESMR: a process framework for calibration dynamics across psychosomatic and psychiatric phenomena (opens in new tab)

The brain can be modeled as a generative system that predicts bodily and environmental input and reduces mismatch through updating and action. From this perspective, stress is treated not as prediction error per se, but as a condition in which mismatch persists without sufficient recalibration. Health is therefore defined not as the absence of symptoms, but as the preservation of recalibrability, whereas psychopathology is conceptualized as the progressive fixation of recalibration failure. T...