Altered anterior cingulate cortex functional connectivity in treatment-naïve obsessive-compulsive disorder: a resting-state fMRI study (opens in new tab)

ObjectiveTo investigate the anterior cingulate cortex (ACC) resting-state functional connectivity patterns in OCD patients who have not yet received therapy and analyze how they relate to the intensity of their clinical symptoms.MethodsResting-state fMRI data were acquired from 46 medication-naïve participants with OCD and 33 demographically comparable neurotypical control subjects. The region of focus for the seed-based whole-brain functional connectivity investigation was bilateral ACC. Rel...