Neural correlates of altered loss aversion in alcohol use disorder: preliminary evidence of sex-related differences from 18F-FDG-PET imaging (opens in new tab)

Previous findings suggest that the altered punishment sensitivity displayed by individuals with Alcohol Use Disorder (AUD) might reflect lower levels of loss aversion (LA), i.e., the tendency to overweigh negative relative to positive choice consequences. However, whether lower LA represents a core facet of abnormal decision-making in AUD, rather than a secondary consequence of defective executive functioning, remains debated. We used a gambling task to compare LA across 22 AUD patients and 1...