Comparative efficacy and cognitive safety of magnetic seizure therapy and electroconvulsive therapy in major depressive disorder: a systematic review and meta-a... (opens in new tab)

BackgroundMajor depressive disorder (MDD) necessitates treatments that balance efficacy with tolerability. Electroconvulsive therapy (ECT) is highly effective but limited by cognitive side effects. Magnetic seizure therapy (MST), a more focal convulsive therapy, may offer a superior safety profile. This systematic review and meta-analysis directly compares the efficacy and cognitive safety of MST and ECT for MDD.MethodsWe systematically searched PubMed, Embase, Cochrane CENTRAL, Web of Scienc...