Pancreatic Cancer Cell Death Triggered by Caspase‑8 Blockade in Preclinical Models (opens in new tab)

KRAS‑mutant pancreatic cancer relies on caspase‑8 to evade necroptosis, according to a new study. Blocking caspase‑8 triggers cell death in mouse models and patient‑derived organoids, revealing a promising therapeutic vulnerability. The post appeared first on .