Is fever a symptom of glycine deficiency? (opens in new tab)

<p>A 2022 LessWrong post on <a href="https://www.lesswrong.com/posts/sksP9Lkv9wqaAhXsA/orexin-and-the-quest-for-more-waking-hours">orexin and the quest for more waking hours</a> argues that orexin agonists could safely reduce human sleep needs, pointing to short-sleeper gene mutations that increase orexin production and to cavefish that evolved heightened orexin sensitivity alongside an 80% reduction in sleep. Several commenters discussed clinical trials, embryo selection, and the evolutionar...