A network-based map of the chemical exposome connects molecular interactions to public health (opens in new tab)

Chemical exposures significantly affect individual and public health, yet there is no unifying framework describing how diverse chemical compounds may interfere with biological processes and contribute to disease risk. Here, we use a network-based approach to construct a comprehensive map linking 9887 exposures through their shared genetic effects. This map can be used to define classes of exposures that affect common biomolecular processes, even when they are chemically distinct. We find tha...