Nanozyme-engineered liners for proactive prevention of wear particle-induced osteolysis (opens in new tab)

Wear particle-induced osteolysis (WPO), primarily caused by particles generated from implants under mechanical loading, remains a major barrier to the long-term success of prosthetic implants. Traditional strategies to address WPO have largely focused on reducing wear generation, rather than mitigating the immunostimulatory effects elicited by wear particles. However, the limited scope of mechanical enhancement and the inevitable generation of wear particles shift increasing attention toward ...