The hippocampus becomes topographically and functionally specialized along the longitudinal axis with development (opens in new tab)

The human hippocampus exhibits distinct genetic, cellular, and connectivity profiles along its anterior–posterior long-axis, resulting in a differential sensitivity to visuospatial information. Long-axis development, therefore, may contribute to developmental increases in visuospatial memory capacity. To test this, we developed and applied a precision functional mapping technique to identify functional systems in the hippocampus of single subjects using BOLD-fMRI (N = 471, aged 5–21). We disc...