Nanotechnology-mediated precision delivery of mRNA (opens in new tab)

Messenger RNA-based therapeutics have been successful in preventing and treating various diseases. Nonetheless, these therapies still face difficulties in achieving specific delivery to organs, tissues and cells, which are exacerbated by the need to overcome multilevel biological barriers and intrinsically complex physiological disease characteristics. Several approaches are being developed to overcome these challenges, including optimizing administration routes, enhancing targeting abilities...