DynamicAtlas: a morphodynamic atlas for Drosophila development (opens in new tab)

Living organisms develop their shape through the interplay of gene expression and mechanics. While atlases of static samples characterize cell fates and gene regulation, understanding dynamic shape changes requires live imaging. Here we present DynamicAtlas: a ‘morphodynamic atlas’ of live and static datasets from 500 Drosophila melanogaster embryos (wild type and 18 mutants), aligned to a common morphological timeline. Surprisingly, characterizing wild-type surface tissue flows reveals disti...