Structural insights into predicted protein–protein interactions and protein complexes in the human proteome (opens in new tab)

Large-scale computational predictions of human protein-protein interactions (PPIs) have recently enabled systematic mapping of the human interactome at near-atomic resolution. In our previous work, we reported nearly 18,000 high-confidence predicted PPIs, along with selected examples that demonstrated the ability of these predictions to reveal both pairwise associations across diverse pathways and multi-subunit complex organization. Here, we extend that study by presenting additional examples...