Predicting visual mental imagery: structural and transcriptomic signatures in the human brain (opens in new tab)

Visual mental imagery (VMI) vividness varies substantially across individuals, yet the structural and molecular bases of this variability remain elusive. A central debate concerns whether VMI ability depends primarily on early visual cortex (V1) or arises from distributed higher-order cortical systems. Here, in a cohort of 229 adults, we apply parcel-wise cortical morphometric modeling with 20-fold cross-validation with random splits to predict individual differences in VMI ability. We show t...