Comprehensive analysis of interactions between brain aging and late-onset psychoses using heuristic mapping models (opens in new tab)

Advanced brain aging is closely associated with late-onset psychoses, including bipolar disorder(BD), schizophrenia(SP), and major depressive disorder(MDD). Studies have shown that neuroimmune homeostasis imbalance plays an important role in the progression of these conditions. However, potential pathogenetic features of these different late-onset psychoses in the context of brain aging, as well as the crosstalk between aging and these psychiatric conditions, remain to be fully elucidated. To...