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Smallpox, Inoculation, and the Revolutionary War (U.S. National Park Service) (opens in new tab)

During the 1700s, smallpox raged through the American colonies and the Continental Army. Smallpox impacted the Continental Army severely during the Revolutionary War, so much so that George Washington mandated inoculation for all Continental soldiers in 1777. Just fifty-six years earlier, in 1721, Bostonian doctors and clergy introduced the procedure to the American colonies. Without the vision and determination of these early Bostonians in normalizing inoculation, Washington may not have mad...

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