Polycatechol-based iron predators disrupt fungal iron homeostasis to drive selective antifungal action (opens in new tab)

Proceedings of the National Academy of Sciences, Volume 123, Issue 25, June 2026. SignificanceA class of cationic polycatechols, termed fungal iron predators (FIPs), presents a potent solution to drug-resistant fungal infections. Diverging from conventional membrane-disrupting agents, FIPs infiltrate fungal cells and selectively ...