Optimizing Dog Health Through Longevity Science (Kaeberlein) (opens in new tab)

The core thesis of this research centers on utilizing companion dogs (Canis lupus familiaris) as a high-fidelity, translationally accelerated model in geroscience to evaluate longevity therapeutics like rapamycin. Domestic canines present an optimal intermediate model between laboratory rodents and humans because they age approximately seven to ten times faster than humans, express equivalent age-related pathologies (such as cardiomyopathy, cognitive decline, and neoplasia), exhibit massive p...