What the First Human Rapamycin Trials Found (HealthSpan) (opens in new tab)

From: For two decades, rapamycin has been the most consistently life-extending compound ever tested in animals. The PEARL trial just dropped one-year human data. Early cardiovascular signals are emerging. Researchers are now looking at long COVID, chronic fatigue, ovarian aging — conditions where mTOR dysregulation may be at the center of what’s going wrong. The question has finally shifted from “does this extend lifespan in mice” to “are we seeing real healthspan benefits in humans.” We spen...