There are numerous betting options on Sunday during the Week 10 NFL schedule, and the latest bet365 bonus code **CBSBET365 **gives new users $200 in bonus bets after placing a first wager of $5 or more. The 49ers will host the Rams at 4:25 p.m. ET, with Los Angeles listed as a 5.5-point road favorite. Elsewhere, the Seahawks are 6.5-point favorites against the Cardinals and the Chargers are 2.5-point favorites against the Steelers on Sunday Night Football in a game with an over-under of 44.5.

SportsLine’s proven computer model is backing the Under (49.5) in 49ers vs. Rams and is also targeting the Seahawks and Steelers to cover the spread in their respective matchups. Claim the latest bet365 bonus code here:

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The model, which simulates every game 10,000 times, has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks. Anybody following its college football betting picks at sportsbooks and on betting sites could have seen strong returns. Bet games at bet365 here:

Sunday’s top picks, best bets

• Under 49.5 in 49ers vs. Rams
• Seahawks -6.5 vs. Cardinals
• Steelers +2.5 vs. Chargers

Combining the model’s three picks into a three-leg parlay at bet365 would result in a payout of +595 (risk $100 to win $595). Bet it at bet365 here:

Under 49.5 in 49ers vs. Rams

These division rivals have gone Under in nine of their last 12 meetings in San Francisco, including a 12-6 final last December in a game that had an over/under of 48.5. They combined for 49 points when they met in Los Angeles on Oct. 2, but the total closed at 43.5 points in that matchup, and it took overtime to get to 49. Given the 49ers’ slew of injuries on both sides of the ball and the inflated total compared to their first meeting of the year, the model has the Under cashing in 63% of simulations. Bet 49ers vs. Rams at bet365 here:

Seahawks -6.5 vs. Cardinals

Seattle has dominated this rivalry in recent years, going 9-1 straight up and 8-2 against the spread in the last 10 meetings. The Seahawks have won the last three games at home by 10 points, and they are riding a three-game winning streak entering this contest. Arizona continues playing without starting quarterback Kyler Murray (foot), so the model has Seattle covering 56% of the time. Bet Seahawks vs. Cardinals at bet365 here:

Steelers +2.5 vs. Chargers

This has been another lopsided series of late, with Pittsburgh winning 11 of the last 15 matchups and covering the spread in seven of the last eight meetings hosted by the Chargers. Los Angeles could be without three starters along the offensive line, which does not bode well against a Pittsburgh defense that racked up 19 total pressures and five sacks in a win over Indianapolis last week. The Steelers rank second in the NFL in turnover differential, and Chargers quarterback Justin Herbert has thrown an interception in three straight games, which are all reasons why the model has Pittsburgh covering the spread in 54% of simulations. Bet Steelers vs. Chargers at bet365 here:

Looking for more Week 10 NFL picks?

You’ve seen the model’s best bets for Sunday. Now, get against the spread, total and money-line picks for every NFL game here, all from the model that’s simulated every game 10,000 times.