By Jessica Hagen , Executive Editor | December 18, 2025 | 12:26 PM

Photo: Douglas Sacha/Getty Images
Neurotechnology company CranioSense has been awarded approximately $5.5 million in non-dilutive funding through the NIH Blueprint MedTech Program and the U.S. Department of Defense’s Joint Warfighter Medical Research Program (JWMRP).
WHAT IT DOES
The Boston-based company is developing an intracranial pressure diagnostic and monitoring system that uses near-infrared optical sensors and proprietary algorithms, enabling patient…
By Jessica Hagen , Executive Editor | December 18, 2025 | 12:26 PM

Photo: Douglas Sacha/Getty Images
Neurotechnology company CranioSense has been awarded approximately $5.5 million in non-dilutive funding through the NIH Blueprint MedTech Program and the U.S. Department of Defense’s Joint Warfighter Medical Research Program (JWMRP).
WHAT IT DOES
The Boston-based company is developing an intracranial pressure diagnostic and monitoring system that uses near-infrared optical sensors and proprietary algorithms, enabling patients with traumatic brain injury to be tested for elevated intracranial pressure without the need to drill a hole in the skull or insert a sensor into the brain.
The company’s system uses a forehead patch, two clip-on sensors and a handheld device to measure intracranial pressure, which, if elevated, can lead to serious health issues such as brain damage, coma or death.
CranioSense said the NIH and JWMRP grants will fund the company’s initiatives that link its defense-driven work to its goal of improving brain pressure assessment in all levels of civilian care.
"These awards will support device development and pivotal validation, moving CranioSense decisively toward market launch," Ryan Myers, CEO and cofounder of CranioSense, said in a statement.
"The Blueprint MedTech and JWMRP programs represent two sides of the same mission: enabling better neurologic care anywhere and everywhere it is needed."
MARKET SNAPSHOT
In April, CranioSense was named the overall winner of the University of Massachusetts Lowell’s $200K M2D2 Challenge. The event was hosted by the University of Massachusetts’ Medical Device Development (M2D2) Centre and is an annual competition that is now in its 14th year.
The competition focuses on the medical technology and biotechnology sectors globally and aims to identify and reward ground-breaking and disruptive startup companies.
Other companies using non-invasive methods to measure intracranial pressure include Sonovum, which uses ultrasound-based signals and algorithms to capture measurements.
UK-based Crainio shines low-power infrared light onto an individual’s scalp and detects pulse signals reflected from the brain. Algorithms then convert the measured pulse signal into an intracranial pressure estimate.
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