Unveiling the cut-and-repair cycle of designer nucleases in human stem and T cells via CLEAR-time dPCR
nature.com·6h
🧩DNA assembly
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Reimagining biocatalysis: Turning DNA phosphates into chiral catalysts
phys.org·25m
⚗️Enzyme Engineering
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Short heat shock factor A2 regulates heat resistance and growth balance in <i>Arabidopsis</i>
elifesciences.org·17h
🧩DNA assembly
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Genomic and epigenomic maps of mouse centromeres and pericentromeres
nature.com·3h
🧩DNA assembly
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Better understanding of laboratory animal genetics will improve reproducibility
journals.plos.org·4d
📈Biostatistics
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Complex de novo structural variants are an underestimated cause of rare disorders
nature.com·6h
🧩DNA assembly
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An enzymatic cascade enables sensitive and specific proximity labeling proteomics in challenging biological systems
nature.com·3h
📊Bioinformatics
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A New Startup Wants to Edit Human Embryos
📊Bioinformatics
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Geonum – geometric number library for unlimited dimensions with O(1) complexity
🧮Computational Biology
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Live Conversational Threads: Not an AI Notetaker
lesswrong.com·13h
🎨Computational Art
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Disruption to science will last longer than the US government shutdown
arstechnica.com·3h
🧮Computational Biology
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CRISPR targeting of H3K4me3 activates gene expression and unlocks centromere-proximal crossover recombination in Arabidopsis
nature.com·3d
🧩DNA assembly
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One molecule could usher revolutionary medicines for cancer, diabetes and genetic disease — but the US is turning its back on it
🪢Protein Folding
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AI-guided enzyme discovery enables 98.6% breakdown of polyurethane foam in hours
phys.org·55m
⚗️Enzyme Engineering
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ClairS-TO: a deep-learning method for long-read tumor-only somatic small variant calling
nature.com·3d
📊Bioinformatics
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Foundation model reveals how cells are organized in tissues
phys.org·1h
🧮Computational Biology
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More than a structural bystander: Vinculin's unexpected role in cellular mechanical memory
phys.org·1h
🪢Protein Folding
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SARS-CoV-2 NSP14 inhibitor exhibits potent antiviral activity and reverses NSP14-driven host modulation
nature.com·3h
🪢Protein Folding
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Structure of the human astrovirus capsid spike in complex with the neonatal Fc receptor
nature.com·6h
📊Bioinformatics
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