CRISPR targeting of H3K4me3 activates gene expression and unlocks centromere-proximal crossover recombination in Arabidopsis
nature.com·2d
🧩DNA assembly
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Better understanding of laboratory animal genetics will improve reproducibility
journals.plos.org·3d
📈Biostatistics
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A New Startup Wants to Edit Human Embryos
wired.com·3d
📊Bioinformatics
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A high-performance biocatalytic platform for green hydrocarbon production
phys.org·1d
⚗️Enzyme Engineering
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ClairS-TO: a deep-learning method for long-read tumor-only somatic small variant calling
nature.com·2d
📊Bioinformatics
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Research roundup: 6 cool science stories we almost missed
arstechnica.com·22h
🌊Diffusion Models
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OpenSpliceAI provides an efficient modular implementation of SpliceAI enabling easy retraining across nonhuman species
elifesciences.org·3d
📊Bioinformatics
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Vaccination against ASI
lesswrong.com·1d
🌐IoT
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One molecule could usher revolutionary medicines for cancer, diabetes and genetic disease — but the US is turning its back on it
🪢Protein Folding
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Integrative brain omics approach highlights sn-1 lysophosphatidylethanolamine in Alzheimer’s dementia
nature.com·2d
🧮Computational Biology
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Modeling and addressing on-target/off-tumor toxicity of claudin 18.2 targeted immunotherapies
nature.com·18h
🧮Computational Biology
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Gene modification enables more functional liver cells from stem cells
phys.org·4d
🧩DNA assembly
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Discovery of obesity genes through cross-ancestry analysis
nature.com·3d
📊Bioinformatics
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Rare lost allele that boosts soybean seed protein identified
phys.org·1d
📊Bioinformatics
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Rescue of imprinted genes by epigenome editing in human cellular models of Prader-Willi syndrome
nature.com·5d
🧩DNA assembly
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AI-guided analysis assigns amino acid-level roles in protein design
phys.org·2d
🧮Computational Biology
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On-target off-tumor toxicity of claudin18.2-directed CAR-T cells in preclinical models
nature.com·18h
📊Bioinformatics
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Dissociation of the nuclear basket triggers chromosome loss in aging yeast
elifesciences.org·3d
🧩DNA assembly
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