bioRxiv: Bioinformatics Preprints

Pillbox: A Leakage-Aware Foundation-Model Predictor and Lineage-Ceiling Diagnostic for Cancer Drug Response

biorxiv.org·

OCOO-T : A SIMPLE AND SCALABLE VIRTUAL CELL MODEL FOR TRANSCRIPTIONAL PERTURBATION RESPONSE PREDICTION

biorxiv.org·

GeroQubit: a lightweight, honesty-first de-novo design platform for geroscience-native small molecules with calibrated uncertainty

biorxiv.org·

An AI-Powered Trisomy 21 Research Assistant

biorxiv.org·

Calibrated Uncertainty Quantification for Patient-Level AML Drug Sensitivity Prediction Using Split Conformal Prediction

biorxiv.org·

DivQuant: Estimation of Species Richness and Entropy from Small Samples

biorxiv.org·

Revealing trajectories of multi-modal voxel-level changes in neurodegenerative diseases using latent event mapping

biorxiv.org·

TMO: ASYMMETRIC CROSS-MODAL ATTENTION FOR LEARNINGCELL-STATE-DEPENDENT REGULATORY LAGS FROM SINGLE-CELL MULTIOMIC DATA

biorxiv.org·

ANCHOR: haplotype-aware allelic and isoform inference from single-cell long-read RNA sequencing with de novo variant calling

biorxiv.org·

VFUSE: Virulent Feature Understanding with Sparse autoEncoders

biorxiv.org·

TifBERT: a self-supervised foundation model for normalization-robust bulk RNA-seq representation learning

biorxiv.org·

A high-quality chromosome-scale reference genome assembly for Asparagus racemosus var. CIM-Shakti (Shatavari), a medicinal plant of Ayurvedic importance

biorxiv.org·

Combinatorial docking and molecular generation to navigate over 100-billion molecules for prospective ligand discovery

biorxiv.org·

HoloCell: A Generative Foundation Model for Holistic Cellular Modeling

biorxiv.org·

Robust semi-supervised scRNA-seq integration from virtual adversarial learning

biorxiv.org·

Sequence-Based Therapeutic Peptide Classification with Augmented Negative Sampling

biorxiv.org·

HOMED enables hierarchical and multimodal optimization of DNA methylation deconvolution across tissues

biorxiv.org·

A multi-agent system for spine MRI report generation from multi-sequence imaging

STITCH links cellular morphology and gene expression in spatial transcriptomics

Pillbox: A Leakage-Aware Foundation-Model Predictor and Lineage-Ceiling Diagnostic for Cancer Drug Response

OCOO-T : A SIMPLE AND SCALABLE VIRTUAL CELL MODEL FOR TRANSCRIPTIONAL PERTURBATION RESPONSE PREDICTION

GeroQubit: a lightweight, honesty-first de-novo design platform for geroscience-native small molecules with calibrated uncertainty

An AI-Powered Trisomy 21 Research Assistant

Calibrated Uncertainty Quantification for Patient-Level AML Drug Sensitivity Prediction Using Split Conformal Prediction

DivQuant: Estimation of Species Richness and Entropy from Small Samples

Revealing trajectories of multi-modal voxel-level changes in neurodegenerative diseases using latent event mapping

TMO: ASYMMETRIC CROSS-MODAL ATTENTION FOR LEARNINGCELL-STATE-DEPENDENT REGULATORY LAGS FROM SINGLE-CELL MULTIOMIC DATA

ANCHOR: haplotype-aware allelic and isoform inference from single-cell long-read RNA sequencing with de novo variant calling

VFUSE: Virulent Feature Understanding with Sparse autoEncoders

TifBERT: a self-supervised foundation model for normalization-robust bulk RNA-seq representation learning

A high-quality chromosome-scale reference genome assembly for Asparagus racemosus var. CIM-Shakti (Shatavari), a medicinal plant of Ayurvedic importance

Combinatorial docking and molecular generation to navigate over 100-billion molecules for prospective ligand discovery

HoloCell: A Generative Foundation Model for Holistic Cellular Modeling

Robust semi-supervised scRNA-seq integration from virtual adversarial learning

Sequence-Based Therapeutic Peptide Classification with Augmented Negative Sampling

HOMED enables hierarchical and multimodal optimization of DNA methylation deconvolution across tissues

Folding the unfoldable 2: using AlphaFold and ESMFold to explore spurious proteins