Frontiers in Bioinformatics

Hydrogen sulfide modulates gene networks in hypoxia/reoxygenation-stressed trophoblasts: insights from transcriptome profiling

Frontiers·

Real-world chronic recordings from implantable adaptive deep brain stimulation systems for Parkinson’s disease motor state classification

Frontiers·

Molecular Dynamics–Based validation of a quinazoline-based KRAS inhibitor (C9) identified through QSAR-guided discovery

Frontiers·

A foundational quantum framework for multi-pattern string matching in k-mer detection

Frontiers·

CapMux: a Snakemake pipeline for early demultiplexing of split-pool scRNA-seq data into sample-resolved outputs

Frontiers·

Computational validation and network pharmacology reveal the cardioprotective and hypolipidemic potential of Arisaema Jacquemontii Blume via molecular docking, metadynamics, DFT, and MM/PBSA analyses

Frontiers·

Explainable machine learning-based identification of transcriptomic biomarkers in CD1c+ dendritic cells for non-infectious uveitis: an integrative analysis of bulk RNA-seq data

Frontiers·

Polygenic modeling of genetic effects on both phenotypic mean and variance: distributional regression for BMI, blood and urine biomarkers in the UK Biobank

Frontiers·

Unbiased distance correlation with sample-size-aware confidence bounds for comparative omics network analysis

Frontiers·

CMA-DTI: a cross-modal fusion and attentive interaction network for interpretable drug-target interaction prediction

Frontiers·

An integrative machine learning, explainable AI, molecular simulation, and cytotoxicity validation framework for the discovery of selective SIRT1 inhibitors against triple negative breast cancer

Frontiers·

Pharmacokinetics, molecular docking, and molecular dynamics simulation unveil novel lichen-derived scaffolds targeting PBP2a MRSA

Frontiers·

A dual functional inhibitory molecule to combat GyrA-ParC and associated mutants in fluoroquinolone-resistant Shigella flexneri causing shigellosis: an ML guided and quantum simulation-based in silico approach

Frontiers·

Harnessing cutting-edge techniques to identify novel gene expression signatures in acute myeloid leukemia patients

Frontiers·

Machine learning-based classification of COVID-19 severity using respiratory microbiome profiles from shotgun metagenomic sequencing

Frontiers·

Integrative multi-cohort analysis of DNA methylation profiles for pancreatic ductal adenocarcinoma biomarker discovery and prognosis

Frontiers·

Association of FCRL3 gene variants with rheumatoid arthritis susceptibility in the indian population: a combined case-control and in- silico analysis

Frontiers·

Editorial: Clinical prediction models in cancer through bioinformatics

RNApedia: a database of structural protein–RNA interactions

Hydrogen sulfide modulates gene networks in hypoxia/reoxygenation-stressed trophoblasts: insights from transcriptome profiling

Real-world chronic recordings from implantable adaptive deep brain stimulation systems for Parkinson’s disease motor state classification

Molecular Dynamics–Based validation of a quinazoline-based KRAS inhibitor (C9) identified through QSAR-guided discovery

A foundational quantum framework for multi-pattern string matching in k-mer detection

CapMux: a Snakemake pipeline for early demultiplexing of split-pool scRNA-seq data into sample-resolved outputs

Computational validation and network pharmacology reveal the cardioprotective and hypolipidemic potential of Arisaema Jacquemontii Blume via molecular docking, metadynamics, DFT, and MM/PBSA analyses

Explainable machine learning-based identification of transcriptomic biomarkers in CD1c+ dendritic cells for non-infectious uveitis: an integrative analysis of bulk RNA-seq data

Polygenic modeling of genetic effects on both phenotypic mean and variance: distributional regression for BMI, blood and urine biomarkers in the UK Biobank

Unbiased distance correlation with sample-size-aware confidence bounds for comparative omics network analysis

CMA-DTI: a cross-modal fusion and attentive interaction network for interpretable drug-target interaction prediction

An integrative machine learning, explainable AI, molecular simulation, and cytotoxicity validation framework for the discovery of selective SIRT1 inhibitors against triple negative breast cancer

Pharmacokinetics, molecular docking, and molecular dynamics simulation unveil novel lichen-derived scaffolds targeting PBP2a MRSA

A dual functional inhibitory molecule to combat GyrA-ParC and associated mutants in fluoroquinolone-resistant Shigella flexneri causing shigellosis: an ML guided and quantum simulation-based in silico approach

Harnessing cutting-edge techniques to identify novel gene expression signatures in acute myeloid leukemia patients

Machine learning-based classification of COVID-19 severity using respiratory microbiome profiles from shotgun metagenomic sequencing

Integrative multi-cohort analysis of DNA methylation profiles for pancreatic ductal adenocarcinoma biomarker discovery and prognosis

Association of FCRL3 gene variants with rheumatoid arthritis susceptibility in the indian population: a combined case-control and in- silico analysis

NbBayesLM: bayesian prediction of nanobody thermostability using protein language model