✂ Polyadenylation - pfh · Scour

Resolving paclitaxel efficacy 📐edgeR

·10h

ACTB methylation regulates SMARCA4 genomic occupancy to promote translation and reduce adhesion in colorectal cancer cells [RESEARCH] 🧬Bioconductor

genome.cshlp.org·6d

Expanding the genetic code with diverse backbone structures across diverse sequence contexts 🧬Genomics

biorxiv.org·4d

RNA-induced PRC2 inhibition depends on the sequence of bound RNA 🧬RNA-Seq

MOSAIC: Codon Harmonization of Monte Carlo-Based Simulated Annealing for Linked Codons in Heterologous Protein Expression 📄FASTQ

Genome editing of phylogenetically distinct bacteria using cross-species retron-mediated recombineering 🧬Genomics

·1d

spRefine denoises and imputes spatial transcriptomic data with a reference-free framework powered by genomic language model [METHOD] 🗺️Spatial Transcriptomics

genome.cshlp.org·6d

ProNA3D: Distance-Based Analysis of Nucleic Acid-Containing Interfaces 📄FASTQ

biorxiv.org·3d

Ubiquitination of glycogen and metabolites in cells and tissues 🔥ComplexHeatmap

·2d

Copy-as-Decode: Grammar-Constrained Parallel Prefill for LLM Editing 🔲Zarr

Discovery of molecular glues that bind FKBP12 and structurally distinct targets using DNA-encoded libraries 🧬Bioconductor

High-fidelity bidirectional translation between single-cell transcriptomes and DNA methylomes with scBOND [METHOD] 📦Pseudobulk

genome.cshlp.org·6d

Reference-free discovery with barcoded single-cell sequencing 🔬Single-cell RNA-Seq

·2d

A systems view on DNA damage response kinetics in Tetrahymena [RESOURCES] 📐edgeR

genome.cshlp.org·6d

Caspase 5c amplifies Wnt via APC cleavage to promote intestinal homeostasis 📐edgeR

·2d

Enzymatic control of enantioselective dimeric cyclotryptamine alkaloid biosynthesis in Calycanthaceae plants 🔬Seurat

·1d

Haplotype-resolved telomere-to-telomere genome of Aphelenchus avenae implicates P5CS in nematode desiccation stress response [RESEARCH] 🔥ComplexHeatmap

genome.cshlp.org·6d

Author Correction: Combination of PARP and KRAS G12D inhibitors enhances therapeutic efficacy by exploiting vulnerabilities in PDAC 📄FASTQ

Deeper is not always better in plasma proteomics 📐edgeR

·2d

Regulation for differential control 📊Differential Expression

·2d

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