Cell Chemical Biology · Scour

An interactive resource mapping the proteome and reactive cysteine landscape across the NCI-60 reveals cell and tissue-specific profiles

Fluorogenic CRISPR for DNA imaging in live mammalian cells

Scaffolding-dependent CASP1 constrains excessive cell-intrinsic inflammatory signaling in leukemia

Adenosine signaling as a hub for the action of novel antidepressant strategies

The interplay between autophagy and unconventional secretion in neurodegeneration

Suppression of pain transmission and behavior by inhibition of peripheral diacylglycerol metabolism

Mechanistic diversity of Bacteroides fragilis toxins and neutralization with single domain antibody

Cutting without cleaving: How caspase-1 shapes leukemia beyond enzymatic activity

1-deoxysphingolipids dysregulate membrane properties and cargo trafficking in the early secretory pathway

Photo-proximity labeling in live primary neurons identifies an AMPA-receptor signal transducer in homeostatic synaptic plasticity

Single-cell glycome and transcriptome profiling enabled by a library of anti-glycan antibodies

Linked-domain inhibitors designed to block UBE2D induce the unfolded protein response

Bugs delivering drugs: Listeria monocytogenes-mediated cytotoxin delivery enhances anti-tumor activity in colorectal cancer

Optogenetic control of biomolecular organization reveals distinct roles of phase separation in RTK signaling

Transcriptional restart: A new role for PARylation in overcoming DNA damage

Two genomes, one destiny: Mitophagy at the crossroads of inheritance and disease

Targeted inhibition of mu-opioid receptors in neuronal subpopulations by membrane-tethered Naloxo-DART antagonists

Immunity in motion: The role of mechanics in macrophage biology

Phytate enhances gut Parasutterella colonization to alleviate radiation injury

Peptide passports: Programmable import fuels novel protein building blocks

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